Systems
LIS (laboratory information systems)
Order out. Validated result back, matched to the order that asked for it.
What this class of system is
A LIS is the software that runs the laboratory and the analysers it manages: order in, validated result out.
orophin speaks HL7 v2 (ORM out, ORU in) and ASTM to the analysers. Out: orders; in: validated results matched to the order. Forge, Atlas, and Sentinel consume and produce the data.
Everything above rides one path. The on-prem orophin agent speaks the protocol on the hospital's own network and opens a single outbound mutually authenticated link to the Pensieve backend. Your network team approves egress.
On the wire
What it emits, and what carries it
The traffic
An order leaves as ORM^O01 or OMG^O19 carrying the accession the laboratory will print on the tube. A validated result returns as ORU^R01, one OBX per analyte, with the unit, the reference range and the abnormal flag the laboratory set. A corrected result returns as a second ORU with a correction status, and the correction has to replace the value the clinician already read.
What breaks here
A result that arrives without the order it answers. Pensieve matches an inbound ORU to the Forge order by accession before it becomes a value in the record, so a result never lands on a patient as an orphan, and a result the bridge cannot match is held with the reason attached rather than dropped. Sentinel watches the thresholds on what does land.
Protocols
The standards this class speaks
Each one is described in full on the standards register, at the anchor named here.
- HL7 v2The dominant hospital messaging standard. orophin sends and receives ADT, ORM / OMG, ORU, DFT, MDM, and SIU. India’s EHR Standards name v2.8.2.
- ASTMThe serial protocol most analysers speak: E1381 transport, E1394 message content, the pair a bench calls LIS02. orophin’s ASTM adapter posts each result against the Forge order.
- MLLP transportThe TCP framing HL7 v2 rides on. A start block, the message, an end block and a carriage return, over a socket. orophin’s MLLP adapter is the transport under every HL7 v2 connection.
- mTLS WebSocket bridgeThe single outbound, mutually authenticated link orophin opens to the Pensieve backend. Both ends verify a certificate, nothing listens on the hospital side, and every row in this register rides it.
- SNOMED / LOINC feedsClinical-term and laboratory / observation coding. An investigation resolves to LOINC and a clinical term to SNOMED CT, which is what makes two analysers comparable.
Members
Systems in this class
22 entries on the register, each at its own anchor.
- Roche cobasASTM E1394 / HL7 v2 over MLLP. In: chemistry and immunoassay results posted against the Forge order.
- Abbott AlinityASTM E1394 / HL7 v2 over MLLP. In: chemistry and immunoassay results to the ordering entry.
- Abbott ArchitectASTM E1394 / HL7 v2 over MLLP. In: chemistry and immunoassay results to the ordering entry.
- Siemens AtellicaASTM E1394 / HL7 v2 over MLLP. In: chemistry and immunoassay results to the ordering entry.
- Siemens ADVIAASTM E1394 / HL7 v2 over MLLP. In: chemistry and haematology results to the ordering entry.
- Beckman Coulter DxHASTM E1394 / HL7 v2 over MLLP. In: haematology results to the ordering entry.
- Beckman Coulter AUASTM E1394 / HL7 v2 over MLLP. In: chemistry results to the ordering entry.
- Sysmex XNASTM E1394 / HL7 v2 over MLLP. In: haematology (CBC/differential) results to the ordering entry.
- Sysmex XTASTM E1394 / HL7 v2 over MLLP. In: haematology results to the ordering entry.
- Mindray BCASTM E1394 / HL7 v2 over MLLP. In: haematology results to the ordering entry.
- Mindray BSASTM E1394 / HL7 v2 over MLLP. In: chemistry results to the ordering entry.
- Horiba YumizenASTM E1394 / HL7 v2 over MLLP. In: haematology results to the ordering entry.
- Transasia / ErbaASTM E1394 / HL7 v2 over MLLP. In: chemistry and haematology results to the ordering entry.
- Bio-Rad D-100ASTM E1394 / HL7 v2 over MLLP. In: HbA1c / HPLC results to the ordering entry.
- Tosoh G8ASTM E1394 / HL7 v2 over MLLP. In: HbA1c / HPLC results to the ordering entry.
- RandoxASTM E1394 / HL7 v2 over MLLP. In: chemistry and immunoassay results to the ordering entry.
- Ortho VitrosASTM E1394 / HL7 v2 over MLLP. In: chemistry and immunoassay results to the ordering entry.
- Nihon Kohden (Celltac)ASTM E1394 / HL7 v2 over MLLP. In: haematology results to the ordering entry.
- Snibe MaglumiASTM E1394 / HL7 v2 over MLLP. In: immunoassay results to the ordering entry.
- Agappe MispaASTM E1394 / HL7 v2 over MLLP. In: chemistry results to the ordering entry.
- DiatronASTM E1394 / HL7 v2 over MLLP. In: haematology and chemistry results to the ordering entry.
- Sysmex CSASTM E1394 / HL7 v2 over MLLP. In: coagulation results to the ordering entry.
What a name in this register means
Compatibility only. Pensieve connects to systems in this class over the protocol they speak. Naming a system describes the connection Pensieve is built to make; it implies no partnership, no certification, and no existing deployment.